Journal article

Changes in long-term survival and neurodevelopmental disability in infants born extremely preterm in the post-surfactant era

RA Boland, JLY Cheong, LW Doyle

Seminars in Perinatology | Published : 2021

Abstract

Extremely preterm birth before 28 weeks’ gestation accounts for less than 1% of births in high-income countries but is associated with high rates of perinatal and infant mortality, and of neurodevelopmental disability in surviving children. Survival rates have increased over time, both overall, and within each week of gestational age since the introduction of exogenous surfactant into clinical care in the early 1990s. However, rates of major neurodevelopmental disability in survivors, whether they be in early childhood or at school-age, have not clearly improved in parallel with the increases in survival. An important strategy to improve survival free of major neurodevelopmental disability i..

View full abstract

Related Projects (1)

Grants

Awarded by Murdoch Children's Research Institute


Funding Acknowledgements

RAB currently holds a Postdoctoral Career Development Award Fellowship funded by the Murdoch Children's Research Institute, Melbourne and by the National Health and Medical Research Council of Australia (Centre of Research Excellence #1153176) . JLC and LWD are supported by National Health and Medical Research Council of Australia (Centre of Clinical Research Excellence #546519; Centre of Research Excellence #1060733 & #1153176) . JLC is supported by the Medical Research Future Fund of Australia (Career Development Fellowship #1141354) . LWD and JLC are sup-ported by the Victorian Government's Operational Infrastruc-ture Support Program.